Article
Dopaminergic polymorphisms in Tourette syndrome: association with the DAT gene (SLC6A3).
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2007
Yoon Dustin Y, Rippel Christopher A, Kobets Andrew J, Morris Christina M, Lee Jennifer E, Williams Phillip N, Bridges Dana D, Vandenbergh David J, Shugart Yin Y, Singer Harvey S
Abstract excerpt
Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by involuntary motor and phonic tics. The pattern of inheritance and associated genetic abnormality has yet to be fully characterized. A dopaminergic abnormality in this disorder is supported by response to specific therapies, nuclear imaging, and postmortem studies. In this protocol, dopaminergic polymorphisms were examined for...
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