Article
A method for the generation of conditional gene repair mutations in mice.
Nucleic acids research - 1 Feb 2001
Dragatsis I, Zeitlin S
Abstract excerpt
Conditional gene repair mutations in the mouse can assist in cell lineage analyses and provide a valuable complement to conditional gene inactivation strategies. We present a method for the generation of conditional gene repair mutations that employs a loxP-flanked (floxed) selectable marker and transcriptional/translational stop cassette (neostop) located within the first intron of a target gene. In the absence...
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