Article
Type B leukemogenic virus has a T-cell-specific enhancer that binds AML-1.
Journal of virology - 1 Mar 2001
Mertz J A, Mustafa F, Meyers S, Dudley J P
Abstract excerpt
Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell tumors in mice. TBLV is highly related to mouse mammary tumor virus (MMTV) except that TBLV long terminal repeats (LTRs) have a deletion of negative regulatory elements and a triplication of sequences flanking the deletion. To determine if the LTR triplication represents a viral enhancer element, we inserted the triplication upstream and downstream...
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