Article
Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.
Journal of virology - 1 Feb 1997
Nieves A, Levy L S, Lenz J
Abstract excerpt
All murine leukemia viruses (MuLVs) and related type C retroviruses contain a highly conserved binding site for the Ets family of transcription factors within the enhancer sequences in the viral long terminal repeats (LTRs). The T-cell lymphomagenic MuLV SL3-3 (SL3-3) also contains a c-Myb binding site adjacent to the Ets site. The presence of this Myb site distinguishes SL3 from most other MuLVs. We tested the...
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