A new leukemogenic retrovirus isolated from tumor cells derived from a radio-induced lymphoma of C57BL/6 mice: analysis of the env and LTR sequences.

doi:10.1016/0168-1702(91)90013-l

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Article

A new leukemogenic retrovirus isolated from tumor cells derived from a radio-induced lymphoma of C57BL/6 mice: analysis of the env and LTR sequences.

Virus research - 1 Mar 1991

Baylac-Kalabokias H, Astier-Gin T, Moynet D, Hernould M, Mamoun R, Legrand E, Guillemain B

Abstract excerpt

We report the cloning and characterization of a new ecotropic provirus encountered in a radio-induced thymic lymphoma of the C57BL/6 mouse. The provirus with an abnormally long LTR was inserted in the chromosomal DNA within the Pvt-1/MLVi-1/Mis-1 region which is a common integration site for MCF virus in mice and for Mo-MuLV in rats. This new ecotropic provirus was molecularly cloned and found to be infectious...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Consensus Sequence
Enhancer Elements, Genetic
Genes, env
Lymphoma
Mice
Mice, Inbred C57BL
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasms, Radiation-Induced

Proviruses

Repetitive Sequences, Nucleic Acid

Restriction Mapping

Retroviridae

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 2042396
DOI: 10.1016/0168-1702(91)90013-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2042396-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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