Article
Genetic heterogeneity in acute myeloid leukemia: maximizing information flow from MuLV mutagenesis studies.
Leukemia - 1 Jul 2000
Largaespada D A
Abstract excerpt
The study of myeloid leukemia induced by slow transforming murine leukemia viruses (MuLV) in the laboratory mouse has led to discovery of many important genes with critical roles in regulating the growth, death, lineage determination and development of hematopoietic precursor cells. This review provides an overview of the susceptible strains and virus isolates that cause acute myeloid leukemia (AML) in mice. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
