Article
Identification of transcriptional regulatory activity within the 5' A-type monomer sequence of the mouse LINE-1 retroposon.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992
Severynse D M, Hutchison C A, Edgell M H
Abstract excerpt
LINE-1 (L1) is a retroposon found in all mammals. In the mouse, approximately 10% of L1 elements are full-length and can be grouped into two classes, A or F, based upon the type of monomer sequence repeated at the 5' end. In order to test for promoter activity in the 5' end of the A-type mouse L1 element, we cloned several different A-monomers into a promoterless chloramphenicol acetyltransferase (CAT) vector....
Topics
- Animals
- Base Sequence
- Cell Line
- DNA
- DNA Transposable Elements
- DNA-Binding Proteins
- Gene Expression Regulation
- HeLa Cells
- Humans
- Mice
- Molecular Sequence Data