Article
A single mutation in one of the CORE elements of Moloney murine leukemia virus reduced binding of a 42-kDa T lymphoma cell nuclear factor but did not affect lymphomagenesis.
Molecular carcinogenesis - 1 Jan 1990
Case R S, Khang Y H, Kumar A, Yuen P H
Abstract excerpt
The genetic determinant responsible for virulence in Moloney murine leukemia virus (MoMuLV) induced T-cell lymphomagenesis has recently been mapped [J Virol 63:471-480, 1989] by homologous genomic fragment exchange between MoMuLV and MoMuLV-TB to the Clal/Xbal at the 3' end of the genome. This re...
Topics
- Animals
- Base Sequence
- Cell Transformation, Viral
- Cloning, Molecular
- DNA Probes
- DNA, Viral
- Enhancer Elements, Genetic
- Lymphoma
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Moloney murine leukemia virus
- Mutation
- Nuclear Proteins
- T-Lymphocytes
- Tumor Cells, Cultured