Point mutations in the Moloney murine leukemia virus enhancer identify a lymphoid-specific viral core motif and 1,3-phorbol myristate acetate-inducible element.

doi:10.1128/JVI.64.2.543-550.1990

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Article

Point mutations in the Moloney murine leukemia virus enhancer identify a lymphoid-specific viral core motif and 1,3-phorbol myristate acetate-inducible element.

Journal of virology - 1 Feb 1990

Speck N A, Renjifo B, Hopkins N

Abstract excerpt

The transcriptional enhancer of the Moloney murine leukemia virus (MoMLV) is organized as a 75-base-pair repeat, and in each copy of the repeat there are multiple binding sites for nuclear factors. We have introduced point mutations into each of the known nuclear factor-binding sites in the MoMLV...

Topics

Animals
Base Sequence
Cell Line
DNA, Viral
Enhancer Elements, Genetic
Genes, Viral
Humans
Mice
Molecular Sequence Data
Moloney murine leukemia virus
Mutation
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Protein-Tyrosine Kinases

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-fos

Proto-Oncogenes

Rats

Source

Open in PubMed Open full text

Identifiers

PMID: 2104942
DOI: 10.1128/JVI.64.2.543-550.1990
PMCID: PMC249142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2104942-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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