Article
Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer.
Cancer research - 15 Dec 2000
Seth P, Lunetta K L, Bell D W, Gray H, Nasser S M, Rhei E, Kaelin C M, Iglehart D J, Marks J R, Garber J E, Haber D A, Polyak K
Abstract excerpt
In recent years, significant effort has been made to identify genes that influence breast cancer risk. Because the high-penetrance breast cancer susceptibility genes BRCA1 and 2 play a role only in a small fraction of breast cancer cases, understanding the genetic risk of the majority of breast cancers will require the identification and analysis of several lower penetrance genes. The estrogen-signaling pathway...
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