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Article

Sulfotransferase (SULT) 1A1 polymorphic variants 1, 2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation.

Molecular pharmacology - 1 Jun 2006

Nagar Swati, Walther Susan, Blanchard Rebecca L

Abstract excerpt

The superfamily of sulfotransferase (SULT) enzymes catalyzes the sulfate conjugation of several pharmacologically important endo- and xenobiotics. SULT1A1 catalyzes the sulfation of small planar phenols such as neurotransmitters, steroid hormones, acetaminophen, and p-nitrophenol (PNP). Genetic polymorphisms in the human SULT1A1 gene define three alleles, SULT1A1*1, *2, and *3. The enzyme activities of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 16517757
DOI: 10.1124/mol.105.019240

Genes

PNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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