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Article

Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy.

Journal of the National Cancer Institute - 6 Nov 2002

Nowell Susan, Sweeney Carol, Winters Maria, Stone Angie, Lang Nicholas P, Hutchins Laura F, Kadlubar Fred F, Ambrosone Christine B

Abstract excerpt

BACKGROUND: Human sulfotransferase 1A1 (SULT1A1) catalyzes the sulfation of a variety of phenolic and estrogenic compounds, including 4-hydroxytamoxifen (4-OH TAM), the active metabolite of tamoxifen. A functional polymorphism in exon 7 of the SULT1A1 gene (SULT1A1*2) has been described that gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12419790
DOI: 10.1093/jnci/94.21.1635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12419790-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy.PMID 12419790Read ↗

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