Article
Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer.
International journal of molecular medicine - 1 Nov 2002
Hou Ming-Feng, Chen Shou-Tung, Chen Jui-Chang, Yeh Kun-Tu, Lee Tai-Ping, Chen Chih-Mei, Shih Mu-Chin, Lin Cheng-Chieh, Chang Jan-Gowth
Abstract excerpt
The estrogen-signaling pathway plays an important role in the pathophysiology of breast cancer, and the sulfotransferase 1A (SULT1A) family has been found to be both downstream targets of tamoxifen and a risk factor of breast cancer. We have used PCR-RFLP and direct sequencing methods to determin...
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