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Article

Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk.

Journal of the National Cancer Institute - 20 Sept 2006

Rebbeck Timothy R, Troxel Andrea B, Wang Yiting, Walker Amy H, Panossian Saarene, Gallagher Stephen, Shatalova Ekaterina G, Blanchard Rebecca, Bunin Greta, DeMichele Angela, Rubin Stephen C, Baumgarten Mona, Berlin Michelle, Schinnar Rita, Berlin Jesse A, Strom Brian L

Abstract excerpt

BACKGROUND: Unopposed estrogen replacement therapy is associated with increased risk of endometrial cancer. To investigate the mechanism of this association, we evaluated whether risk of endometrial cancer was associated with the genotypes involved in steroid hormone metabolism and the duration of exogenous hormone use. METHODS: A population-based case-control study in nine counties of the Philadelphia...

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PMID: 16985250
DOI: 10.1093/jnci/djj360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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