Quantitative trait loci affecting peak bone mineral density in mice.

doi:10.1359/jbmr.1998.13.11.1648

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Article

Quantitative trait loci affecting peak bone mineral density in mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1998

Klein R F, Mitchell S R, Phillips T J, Belknap J K, Orwoll E S

Abstract excerpt

Peak bone mass is a major determinant of risk of osteoporotic fracture. Family and twin studies have found a strong genetic component to the determination of bone mineral density (BMD). However, BMD is a complex trait whose expression is confounded by environmental influences and polygenic inheri...

Topics

Absorptiometry, Photon
Analysis of Variance
Animals
Body Weight
Bone Density
Calcium
Female
Linear Models
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Inbred Strains
Osteoporosis
Phenotype
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 9797472
DOI: 10.1359/jbmr.1998.13.11.1648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9797472-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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