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Article

Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2003

Shultz Kathryn L, Donahue Leah Rae, Bouxsein Mary L, Baylink David J, Rosen Clifford J, Beamer Wesley G

Abstract excerpt

Peak femoral volumetric bone mineral density (femoral bone mineral density) in C57BL/6J (B6) 4-month-old female mice is 50% lower than in C3H/HeJ (C3H) and 34% lower than in CAST/EiJ (CAST) females. Genome-wide analyses of (B6 x C3H)F2 and (B6 x CAST)F2 4-month-old female progeny demonstrated that peak femoral bone mineral density is a complex quantitative trait associated with genetic loci (QTL) on numerous...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12568393
DOI: 10.1359/jbmr.2003.18.2.175

Genes

CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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