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Article

Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.

Molecular and cellular biology - 1 Jun 2005

Mullen Janet R, Nallaseth Ferez S, Lan Yan Q, Slagle Christopher E, Brill Steven J

Abstract excerpt

Genome stability requires a set of RecQ-Top3 DNA helicase-topoisomerase complexes whose sole budding yeast homolog is encoded by SGS1-TOP3. RMI1/NCE4 was identified as a potential intermediate in the SGS1-TOP3 pathway, based on the observation that strains lacking any one of these genes require MUS81 and MMS4 for viability. This idea was tested by confirming that sgs1 and rmi1 mutants display the same spectrum of...

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Share to DNA Helicases
Share to DNA, Single-Stranded
Share to DNA Topoisomerases, Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome, Fungal

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Source

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Identifiers

PMID: 15899853
DOI: 10.1128/MCB.25.11.4476-4487.2005
PMCID: PMC1140617

Genes

RMI1
MUS81
SLX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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