Article
Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE.
Neurology - 26 Dec 2000
Morris H R, Vaughan J R, Datta S R, Bandopadhyay R, Rohan De Silva H A, Schrag A, Cairns N J, Burn D, Nath U, Lantos P L, Daniel S, Lees A J, Quinn N P, Wood N W
Abstract excerpt
Article abstract-Alpha synuclein, tau, synphilin, and APOE genotypes were analyzed in patients with multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) and controls. The predisposing effect of the tau insertion polymorphism to the development of PSP is confirmed. However, no effect of alpha-synuclein, synphilin, or APOE variability on the development of PSP, or of tau, alpha-synuclein, APOE, or...
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