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Article

APOE E4 is a determinant for Alzheimer type pathology in progressive supranuclear palsy.

Neurology - 28 Jan 2003

Tsuboi Yoshio, Josephs Keith A, Cookson Natalie, Dickson Dennis W

Abstract excerpt

OBJECTIVE: To assess demographic and genetic determinants of Alzheimer type pathology in progressive supranuclear palsy (PSP). METHODS: From a total of 173 pathologically proven cases of PSP in the Society for PSP Brain Bank, 143 patients (mean age = 74.4 years, ranging from 42 to 98 years) were suitable for genetic and pathologic study. Senile plaques (SPs) and neurofibrillary tangles (NFTs) were counted in five...

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Source

Identifiers

PMID: 12552038
DOI: 10.1212/01.wnl.0000044340.37138.a9

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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