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Article

Alpha-synuclein A53T mutation is not frequent on a sample of Brazilian Parkinson's disease patients.

Arquivos de neuro-psiquiatria - 1 Jun 2015

Longo Gabriela S, Pinhel Marcela A S, Gregório Michele L, Oliveira Bruno A P, Quinhoneiro Driele C G, Tognola Waldir A, Oliveira Fábio N, Martins Denise Poltronieri, Cezario Sabrina M, Sado Caroline L, Nakazone Marcelo A, Calastri Maria C J, Souza Dorotéia R S

Abstract excerpt

INTRODUCTION: The pathogenesis of Parkinson's disease (PD) involves both genetic susceptibility and environmental factors, with focus on the mutation in the alpha-synuclein gene (SNCA).Objective To analyse the polymorphism SNCA-A53T in patients with familial PD (FPD) and sporadic PD (SPD). METHOD: A total of 294 individuals were studied, regardless of sex and with mixed ethnicity. The study group with 154...

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Identifiers

PMID: 26083886
DOI: 10.1590/0004-282X20150032

Genes

SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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