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Article

Role for phospholipase D in receptor-mediated endocytosis.

Molecular and cellular biology - 1 Jan 2001

Shen Y, Xu L, Foster D A

Abstract excerpt

In response to epidermal growth factor (EGF), the EGF receptor is endocytosed and degraded. A substantial lag period exists between endocytosis and degradation, suggesting that endocytosis is more than a simple negative feedback. Phospholipase D (PLD), which has been implicated in vesicle formation in the Golgi, is activated in response to EGF and other growth factors. We report here that EGF receptor endocytosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11134345
DOI: 10.1128/MCB.21.2.595-602.2001
PMCID: PMC86627

Genes

EGF
PLD1
PLD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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