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Article

Recognition of Nascent RNA by the Human La Antigen: Conserved and Divergent Features of Structure and Function

1 Jan 2001

Abstract excerpt

La is a conserved RNA-binding phosphoprotein that interacts with a large variety of ligands. The most ubiquitous function of La is association with newly synthesized RNA polymerase (Pol) III transcripts via their common UUU-OH 39 termini and stabilization of these against exonucleolytic digestion. Accumulating evidence also indicates an activity for La in internal ribosome entry site-mediated translation in...

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Identifiers

PMID: 11134326
DOI: 10.1128/mcb.21.2.367-379.2001

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