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Article

The La motif and the RNA recognition motifs of human La autoantigen contribute individually to RNA recognition and subcellular localization.

The Journal of biological chemistry - 26 Nov 2004

Horke Sven, Reumann Kerstin, Schulze Christian, Grosse Frank, Heise Tilman

Abstract excerpt

The human La autoantigen (hLa) protein is a predominantly nuclear phosphoprotein that contains three potential RNA binding domains referred to as the La motif and the RNA recognition motifs RRMs 1 and 2. With this report, we differentiated the contribution of its three RNA binding domains to RNA binding by combining in vitro and in vivo assays. Also, surface plasmon resonance technology was used to generate a...

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Source

Identifiers

PMID: 15371415
DOI: 10.1074/jbc.M407504200

Genes

RRM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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