Article
The HLA A2/6802 supertype is associated with reduced risk of perinatal human immunodeficiency virus type 1 transmission.
The Journal of infectious diseases - 1 Feb 2001
MacDonald K S, Embree J E, Nagelkerke N J, Castillo J, Ramhadin S, Njenga S, Oyug J, Ndinya-Achola J, Barber B H, Bwayo J J, Plummer F A
Abstract excerpt
Certain HLAs may, in part, account for differences in human immunodeficiency virus type 1 (HIV-1) susceptibility by presenting conserved immunogenic epitopes for T cell recognition. The HLA supertype A2/6802 is associated with decreased susceptibility to HIV-1 among sex workers. The alleles in this supertype present the same HIV-1 peptide epitopes for T cell recognition in some cases. This study sought to...
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