Article
HLA Class II Antigens and Their Interactive Effect on Perinatal Mother-To-Child HIV-1 Transmission.
PloS one - 1 Jan 2015
Luo Ma, Embree Joanne, Ramdahin Suzie, Bielawny Thomas, Laycock Tyler, Tuff Jeffrey, Haber Darren, Plummer Mariel, Plummer Francis A
Abstract excerpt
HLA class II antigens are central in initiating antigen-specific CD4+ T cell responses to HIV-1. Specific alleles have been associated with differential responses to HIV-1 infection and disease among adults. This study aims to determine the influence of HLA class II genes and their interactive effect on mother-child perinatal transmission in a drug naïve, Mother-Child HIV transmission cohort established in Kenya,...
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