Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA class I supertypes: a revised and updated classification.

BMC immunology - 22 Jan 2008

Sidney John, Peters Bjoern, Frahm Nicole, Brander Christian, Sette Alessandro

Abstract excerpt

BACKGROUND: Class I major histocompatibility complex (MHC) molecules bind, and present to T cells, short peptides derived from intracellular processing of proteins. The peptide repertoire of a specific molecule is to a large extent determined by the molecular structure accommodating so-called main anchor positions of the presented peptide. These receptors are extremely polymorphic, and much of the polymorphism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Antigen Presentation
Share to Binding Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Histocompatibility Antigens Class I

Share to Histocompatibility Testing

Share to Immunodominant Epitopes

Share to Sequence Analysis, Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 18211710
DOI: 10.1186/1471-2172-9-1
PMCID: PMC2245908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA class I supertypes: a revised and updated classification.PMID 18211710Read ↗

A framework to sub-type HLA supertypes.Semantic proximity Read ↗

Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism.Semantic proximity Read ↗

HLA Class I Supertype Classification Based on Structural Similarity.Semantic proximity Read ↗

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes.Semantic proximity Read ↗

HLAsupE: an integrated database of HLA supertype-specific epitopes to aid in the development of vaccines with broad coverage of the human population.Semantic proximity Read ↗

Origins and relatedness of human leukocyte antigen class I allele supertypes.Semantic proximity Read ↗

Structural basis for HLA-A2 supertypes.Semantic proximity Read ↗

A new categorization of HLA DR alleles on a functional basis.Semantic proximity Read ↗

Simultaneous prediction of binding capacity for multiple molecules of the HLA B44 supertype.Semantic proximity Read ↗

Definition of MHC supertypes through clustering of MHC peptide-binding repertoires.Semantic proximity Read ↗

In silico identification of supertypes for class II MHCs.Semantic proximity Read ↗

In silico grouping of peptide/HLA class I complexes using structural interaction characteristics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.