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Article

Origins and relatedness of human leukocyte antigen class I allele supertypes.

Human immunology - 1 Sept 2010

Naugler Christopher

Abstract excerpt

Class I human leukocyte antigen (HLA) alleles can be classified into supertypes based on the epitope specificity of their peptide binding grooves. The evolutionary origin of these supertypes has been the topic of prior research and remains an important question because of the increasing interest in HLA supertypes in the contexts of infection and cancer epidemiology and vaccine development. Here I re-examine the...

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Share to Amino Acid Substitution
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, MHC Class I

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Identifiers

PMID: 20600449
DOI: 10.1016/j.humimm.2010.06.010

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