Article
Characterization of salt-tolerant mutant for enhancement of L-threonine production in Escherichia coli.
Applied microbiology and biotechnology - 1 Nov 2000
Song K H, Lee H H, Hyun H H
Abstract excerpt
Escherichia coli strain HS3, metabolically engineered to have Met(-), AHV(r), Ile(L) and AEC(r) characteristics, produced 58.0 g/l of L-threonine, but it was neither salt-tolerant nor osmotolerant; and the growth and threonine production of the strain were severely inhibited both by the addition of NaCl with a concentration higher than 2% and by the presence of glucose with a concentration higher than 10%....
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