Article
Global analyses of transcriptomes and proteomes of a parent strain and an L-threonine-overproducing mutant strain.
Journal of bacteriology - 1 Sept 2003
Lee Jin-Ho, Lee Dong-Eun, Lee Bheong-Uk, Kim Hak-Sung
Abstract excerpt
We compared the transcriptome, proteome, and nucleotide sequences between the parent strain Escherichia coli W3110 and the L-threonine-overproducing mutant E. coli TF5015. DNA macroarrays were used to measure mRNA levels for all of the genes of E. coli, and two-dimensional gel electrophoresis was used to compare protein levels. It was observed that only 54 of 4,290 genes (1.3%) exhibited differential expression...
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