Improved L-threonine production of Escherichia coli mutant by optimization of culture conditions.

doi:10.1263/jbb.101.127

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Article

Improved L-threonine production of Escherichia coli mutant by optimization of culture conditions.

Journal of bioscience and bioengineering - 1 Feb 2006

Lee Man-Hyo, Lee Hong-Weon, Park Jin-Ho, Ahn Jung-Oh, Jung Joon-Ki, Hwang Yong-Il

Abstract excerpt

L-threonine production was investigated in a minimal salt medium using L-threonine-overproducing Escherichia coli MT201, derived from E. coli K-12. It was observed that dry cell weight reached 12.5 g/l with 15.9 g/lL-threonine. To increase dry cell weight and L-threonine production, the fermentation process was optimized. When biotin was added as growth factor, L-threonine production reached 52.0 g/l from 15.9...

Topics

Air
Bacteriological Techniques
Biotin
Culture Media
Escherichia coli
Industrial Microbiology
Mutation
Oxygen
Salts
Threonine

Source

Open in PubMed

Identifiers

PMID: 16569607
DOI: 10.1263/jbb.101.127

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