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Article

ROSA26 mice carry a modifier of Min-induced mammary and intestinal tumor development.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2000

Kohlhepp R L, Hegge L F, Nett J E, Moser A R

Abstract excerpt

B6.129S7-Gtrosa26 (B6.R26) mice carry a LacZ-neoR insertion on Chromosome (Chr) 6, made by promoter trapping with 129 ES cells. Female C57BL/6J ApcMin/+ (B6Min/+) mice are highly susceptible to intestinal tumors and to the induction of mammary tumors after treatment with ethylnitrosourea (ENU). However, B6.R26/+ Min/+ females develop fewer mammary and intestinal tumors after ENU treatment than do B6 Min/+ mice....

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Identifiers

PMID: 11130972
DOI: 10.1007/s003350010208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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