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Article

Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2016

Van Der Kraak Lauren, Langlais David, Jothy Serge, Beauchemin Nicole, Gros Philippe

Abstract excerpt

Inbred strains of mice differ in susceptibility to colitis-associated colorectal cancer (CA-CRC). We tested 10 inbred strains of mice for their response to azoxymethane/dextran sulfate sodium-induced CA-CRC and identified a bimodal inter-strain distribution pattern when tumor multiplicity was used as a phenotypic marker of susceptibility. The FVB/NJ strain was particularly susceptible showing a higher tumor...

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PMID: 26979842
DOI: 10.1007/s00335-016-9625-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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