Article
Dynamic readjustment of parental methylation patterns of the 5'-flank of the mouse H19 gene during in vitro organogenesis.
The International journal of developmental biology - 1 Oct 2000
Liang L, Kanduri C, Pilartz M, Svensson K, Song J H, Wentzel P, Eriksson U, Ohlsson R
Abstract excerpt
Gametic marks are stably propagated in order to manifest parent of origin-specific expression patterns of imprinted genes in the developing conceptus. Although the character of the imprint has not yet been fully elucidated, there is compelling evidence that it involves a methylation mark. This is exemplified by a region upstream of the H19 gene, which is not only methylated in a parent of origin-specific manner,...
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