Article
Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Nov 2000
van der Kallen C J, Cantor R M, van Greevenbroek M M, Geurts J M, Bouwman F G, Aouizerat B E, Allayee H, Buurman W A, Lusis A J, Rotter J I, de Bruin T W
Abstract excerpt
OBJECTIVE: To search for novel genes contributing to adiposity in familial combined hyperlipidemia (FCH), a disorder characterized by abdominal obesity, hyperlipidemia and insulin resistance, using a 10cM genome-wide scan. DESIGN: Plasma leptin and soluble tumor necrosis factor receptor superfamily members 1A and 1B (sTNFRSF1A and sTNFRSF1B, also known as sTNFR1 and sTNFR2) were analyzed as unadjusted and...
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