Article
Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 2001
Allayee H, de Bruin T W, Michelle Dominguez K, Cheng L S, Ipp E, Cantor R M, Krass K L, Keulen E T, Aouizerat B E, Lusis A J, Rotter J I
Abstract excerpt
Genes contributing to common forms of hypertension are largely unknown. A number of studies in humans and in animal models have revealed associations between insulin resistance, dyslipidemia, and elevated hypertension. To identify genes contributing to blood pressure (BP) variation associated with insulin-resistant dyslipidemia, we conducted a genome-wide scan for BP in a set of 18 Dutch families exhibiting the...
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