Article
LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women.
European journal of clinical investigation - 1 May 2001
Mammès O, Aubert R, Betoulle D, Péan F, Herbeth B, Visvikis S, Siest G, Fumeron F
Abstract excerpt
BACKGROUND: In humans, a mutation of the leptin receptor gene (LEPR) leads to a rare obese syndrome of mendelian inheritance. However, obesity in humans results from interactions between genes and environment, mainly nutritional factors. Variations at the LEPR locus could be involved in the regul...
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