Article
Elevated leptin levels in subjects with familial combined hyperlipidemia are associated with the increased risk for CVD.
Atherosclerosis - 1 Dec 2005
van der Vleuten Gerly M, Veerkamp Mario J, van Tits Lambertus J H, Toenhake Helga, den Heijer Martin, Stalenhoef Anton F H, de Graaf Jacqueline
Abstract excerpt
Familial combined hyperlipidemia (FCH) is characterized by hypercholesterolemia and/or hypertriglyceridemia and is associated with premature cardiovascular disease (CVD). Other features of FCH are obesity and insulin resistance. Serum leptin levels have been associated with obesity, insulin resistance and CVD. The aim of this study was to determine whether increased leptin levels contribute to the FCH phenotype...
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