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Article

Neoplastic transformation and cytogenetic changes after Gamma irradiation of human epithelial cells expressing telomerase.

Radiation research - 1 Jan 2001

Riches A, Peddie C, Rendell S, Bryant P, Zitzelsberger H, Bruch J, Smida J, Hieber L, Bauchinger M

Abstract excerpt

Neoplastic transformation of human epithelial cells by radiation has previously been investigated using cell lines immortalized with viral vectors. There are disadvantages to this approach, and we report here the results of studies using a human retinal pigment epithelial cell line (340RPE-T53) immortalized by treatment with telomerase. After exposure of the cells to fractionated doses of gamma radiation, there...

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Identifiers

PMID: 11121238
DOI: 10.1667/0033-7587(2001)155[0222:ntacca]2.0.co;2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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