Article
Radiation-induced cell transformation: transformation efficiencies of different types of ionizing radiation and molecular changes in radiation transformants and tumor cell lines.
Environmental health perspectives - 1 Aug 1990
Hieber L, Trutschler K, Smida J, Wachsmann M, Ponsel G, Kellerer A M
Abstract excerpt
This study aims to compare the efficiencies of 5.4 keV soft X-rays, alpha-particles, and gamma-rays in transforming C3H 10T1/2 cells and to assess the sequence of cellular and molecular changes during the process of radiation-induced transformation of Syrian hamster embryo (SHE) cells. The somewh...
Topics
- Alpha Particles
- Animals
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Gamma Rays
- Gene Amplification
- Genes, myc
- Genes, ras
- Mutation
- Polymorphism, Restriction Fragment Length
- Relative Biological Effectiveness