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Article

Multistep nature of X-ray-induced neoplastic transformation in mammalian cells: genetic alterations and instability.

Journal of radiation research - 1 Mar 1997

Suzuki K

Abstract excerpt

X-ray-induced neoplastic transformation has been studied in Syrian hamster embryo cells. Unirradiated cells had a limited life span, whereas the irradiated cells escaped senescence, showed altered morphology, and acquired anchorage-independence and tumorigenicity in a stepwise manner during successive transfers after irradiation. Multiple genetic changes may be associated with the expression of various...

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PMID: 9164081
DOI: 10.1269/jrr.38.55

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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