Article
Mutation of Thr445 and Ile500 of initiation factor 2 G-domain affects Escherichia coli growth rate at low temperature.
Biochimie - 1 Dec 2000
Larigauderie G, Laalami S, Nyengaard N R, Grunberg-Manago M, Cenatiempo Y, Mortensen K K, Sperling-Petersen H U
Abstract excerpt
The Escherichia coli protein synthesis initiation factor IF2 is a member of the large family of G-proteins. Along with translational elongation factors EF-Tu and EF-G and translational release factor RF-3, IF2 belongs to the subgroup of G-proteins that are part of the prokaryotic translational apparatus. The roles of IF2 and EF-Tu are similar: both promote binding of an aminoacyl-tRNA to the ribosome and...
Topics
- Amino Acid Sequence
- Cell Division
- Conserved Sequence
- Escherichia coli
- Eukaryotic Initiation Factor-5
- GTP Phosphohydrolases
- Genetic Complementation Test
- Guanosine Triphosphate
- Isoleucine
- Mutation
- Peptide Initiation Factors
- Point Mutation
- Protein Conformation