Article
Structural and functional domains of E coli initiation factor IF2.
Biochimie - 1 Dec 1991
Laalami S, Sacerdot C, Vachon G, Mortensen K, Sperling-Petersen H U, Cenatiempo Y, Grunberg-Manago M
Abstract excerpt
Initiation of translation in prokaryotes requires the participation of at least three soluble proteins: the initiation factors IF1, IF2 and IF3. Initiation factor 2, which is one of the largest proteins involved in translation (97.3 kDa) has been shown to stimulate in vitro the binding of fMet-tRNA(fMet) to the 30S ribosomal subunit. After formation of 70S translation initiation complex, IF2 is believed to...
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