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Article

Translation initiation without IF2-dependent GTP hydrolysis.

Nucleic acids research - 1 Sept 2012

Fabbretti Attilio, Brandi Letizia, Milón Pohl, Spurio Roberto, Pon Cynthia L, Gualerzi Claudio O

Abstract excerpt

Translation initiation factor IF2 is a guanine nucleotide-binding protein. The free energy change associated with guanosine triphosphate hydrolase (GTPase) activity of these proteins is believed to be the driving force allowing them to perform their functions as molecular switches. We examined role and relevance of IF2 GTPase and demonstrate that an Escherichia coli IF2 mutant bearing a single amino acid...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Peptide Chain Initiation, Translational

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Source

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Identifiers

PMID: 22723375
DOI: 10.1093/nar/gks569
PMCID: PMC3439930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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