Article
Mutations in GCD11, the structural gene for eIF-2 gamma in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis.
The EMBO journal - 15 May 1995
Dorris D R, Erickson F L, Hannig E M
Abstract excerpt
Translation initiation factor 2 (eIF-2) in eukaryotic organisms is composed of three non-identical subunits, alpha, beta and gamma. In a previous report, we identified GCD11 as an essential gene encoding the gamma subunit of eIF-2 in the yeast Saccharomyces cerevisiae. The predicted amino acid se...
Topics
- Alleles
- Amino Acid Sequence
- Codon, Initiator
- Conserved Sequence
- DNA-Binding Proteins
- Eukaryotic Initiation Factor-2
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Guanosine Triphosphate
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Open Reading Frames