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Article

Contributions of charged residues in a cytoplasmic linking region to Na channel gating.

Biochimica et biophysica acta - 20 Dec 2000

Miller J R, Patel M K, John J E, Mounsey J P, Moorman J R

Abstract excerpt

Na channels inactivate quickly after opening, and the very highly positively charged cytoplasmic linking region between homologous domains III and IV of the channel molecule acts as the inactivation gate. To test the hypothesis that the charged residues in the domain III to domain IV linker have...

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Identifiers

PMID: 11118539
DOI: 10.1016/s0005-2736(00)00304-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11118539-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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