Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Electrostatic interaction between inactivation ball and T1-S1 linker region of Kv1.4 channel.

Biochimica et biophysica acta - 1 Jan 2012

Fan Zhuo, Ji Xuying, Fu Mingyu, Zhang Wanming, Zhang Du, Xiao Zhongju

Abstract excerpt

Inactivation of potassium channels plays an important role in shaping the electrical signaling properties of nerve and muscle cells. The rapid inactivation of Kv1.4 has been assumed to be controlled by a "ball and chain" inactivation mechanism. Besides hydrophobic interaction between inactivation ball and the channel's inner pore, the electrostatic interaction has also been proved to participate in the "ball and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CHO Cells
Share to Cricetinae
Share to Hydrophobic and Hydrophilic Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Channel Gating

Share to Mammals

Share to Membrane Potentials

Share to Patch-Clamp Techniques

Share to Static Electricity

Source

Identifiers

PMID: 21996039
DOI: 10.1016/j.bbamem.2011.09.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Electrostatic interaction between inactivation ball and T1-S1 linker region of Kv1.4 channel.PMID 21996039Read ↗

Effect of inserting charged peptide at NH(2)-terminal on N-type inactivation of Kv1.4 channel.Semantic proximity Read ↗

A mammalian transient type K+ channel, rat Kv1.4, has two potential domains that could produce rapid inactivation.Semantic proximity Read ↗

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.Semantic proximity Read ↗

Inactivation gating of Kv4 potassium channels: molecular interactions involving the inner vestibule of the pore.Semantic proximity Read ↗

A new mode of regulation of N-type inactivation in a Caenorhabditis elegans voltage-gated potassium channel.Semantic proximity Read ↗

Inactivation gating of Kv7.1 channels does not involve concerted cooperative subunit interactions.Semantic proximity Read ↗

Contributions of charged residues in a cytoplasmic linking region to Na channel gating.Semantic proximity Read ↗

Unmasking subtype-dependent susceptibility to C-type inactivation in mammalian Kv1 channels.Semantic proximity Read ↗

Molecular determinants of U-type inactivation in Kv2.1 channels.Semantic proximity Read ↗

A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation.Semantic proximity Read ↗

Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.Semantic proximity Read ↗

Amino-terminal determinants of U-type inactivation of voltage-gated K+ channels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.