Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism.

The Journal of general physiology - 1 Mar 1997

Bennett E, Urcan M S, Tinkle S S, Koszowski A G, Levinson S R

Abstract excerpt

A potential role for sialic acid in the voltage-dependent gating of rat skeletal muscle sodium channels (rSkM1) was investigated using Chinese hamster ovary (CHO) cells stably transfected with rSkM1. Changes in the voltage dependence of channel gating were observed after enzymatic (neuraminidase)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Southern
Share to Cricetinae
Share to Genetic Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation

Share to Sequence Deletion

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 9089440
DOI: 10.1085/jgp.109.3.327
PMCID: PMC2217074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9089440-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism.PMID 9089440Read ↗

The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function.Semantic proximity Read ↗

Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function.Semantic proximity Read ↗

Effects of Kv1.1 channel glycosylation on C-type inactivation and simulated action potentials.Semantic proximity Read ↗

Contributions of charged residues in a cytoplasmic linking region to Na channel gating.Semantic proximity Read ↗

Broadband Tuning the Voltage Dependence of a Sodium ChannelSemantic proximity Read ↗

Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains.Semantic proximity Read ↗

A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb.Semantic proximity Read ↗

Effects of channel cytoplasmic regions on the activation mechanisms of cardiac versus skeletal muscle Na(+) channels.Semantic proximity Read ↗

A negatively charged residue in the outer mouth of rat sodium channel determines the gating kinetics of the channel.Semantic proximity Read ↗

Isoform-dependent interaction of voltage-gated sodium channels with protons.Semantic proximity Read ↗

A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation.Semantic proximity Read ↗

Two arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamily.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.