Article
Structural rearrangements and insertions of dispersed elements in pericentromeric alpha satellites occur preferably at kinkable DNA sites.
Journal of molecular biology - 5 Jan 2001
Mashkova T D, Oparina N Y, Lacroix M H, Fedorova L I, G Tumeneva I, Zinovieva O L, Kisselev L L
Abstract excerpt
Centromeric region of human chromosome 21 comprises two long alphoid DNA arrays: the well homogenized and CENP-B box-rich alpha21-I and the alpha21-II, containing a set of less homogenized and CENP-B box-poor subfamilies located closer to the short arm of the chromosome. Continuous alphoid fragment of 100 monomers bordering the non-satellite sequences in human chromosome 21 was mapped to the pericentromeric short...
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