Article
Transcription of tandemly repetitive DNA: functional roles.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology - 1 Sept 2015
Biscotti Maria Assunta, Canapa Adriana, Forconi Mariko, Olmo Ettore, Barucca Marco
Abstract excerpt
A considerable fraction of the eukaryotic genome is made up of satellite DNA constituted of tandemly repeated sequences. These elements are mainly located at centromeres, pericentromeres, and telomeres and are major components of constitutive heterochromatin. Although originally satellite DNA was thought silent and inert, an increasing number of studies are providing evidence on its transcriptional activity...
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