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Alpha satellite insertion close to an ancestral centromeric region

2021-03-12

Abstract excerpt

Human centromeres are mainly composed of alpha satellite DNA hierarchically organized as higher-order repeats (HORs). Alpha satellite dynamics is shown by sequence homogenization in centromeric arrays and by its transfer to other centromeric locations, for example during the maturation of new centromeres. We identified during prenatal aneuploidy diagnosis by FISH a de novo insertion of alpha satellite DNA from th...

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Literature Corpus work
d4752d29-0597-5d1e-a0ef-a2ef8fd2d400
DOI
10.1101/2021.03.10.434819
Open publication

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Alpha satellite insertion close to an ancestral centromeric regionDOI 10.1101/2021.03.10.434819
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